Standard vs Intensive Monitoring Post-Myocardial Infarction Looking for New-Onset Atrial Fibrillation (SIMPL-AF) and Predictors of Poor Outcomes (SIMPL-PPO)
Project Lead: Dr. Christopher Cheung, Cardiology Resident, University of British Columbia
Mentors: Dr. Jason G. Andrade, Dr. Andrew D. Krahn, Dr. Marc W. Deyell, Dr. Kenneth G. Gin (all University of British Columbia)
Amount: $25,000 (CANet)
After a myocardial infarction (MI), patients discharged home in sinus rhythm may develop atrial fibrillation (AF) that is asymptomatic, undetected, and under-treated (hereby called “AF post-MI”). By using a non-invasive but intensive monitoring strategy (30-day external cardiac monitor), we hypothesize that AF post-MI will be detected more frequently compared to standard care.
By identifying new-onset AF post-MI, intensive monitoring will likely result in higher rates of oral anticoagulation (OAC) prescription compared to standard care. AF post-MI may also be a novel predictor of re-hospitalization post-MI, and may be a target for early intervention to prevent re-hospitalization and subsequent adverse outcomes.